Estrolog

Question: (Human)
I wanted to order a human product called Estrolog and be able to take advantage of the 15% off I got with this order, however I needed to get a clarification on what Dr Wysong had posted about this product in the write up it said this below, my question is what does he mean by heart disease I have a left dystolic dysfunction which means my left side of my heart is working a bit too hard. I would think too much estrogen can be the ACTUAL cause of this happening. Please if you would tell me if this is a contradiction for my being able to order Estrolog, if I can take this I would want to include this on this order still! I am not sure if estrogen is a good thing or a bad thing for my heart. Please if you would clarify. Thank you.

"Estrolog-type phytoestrogens have been used since the 1950's in Europe and are highly successful and safe. The only possible contraindications would be in the presence of pregnancy, lactation, estrogen-dependent tumors and heart disease" from this link - http://www.wysonghealth.net/products/documents/monographs/legacy/ESTROLOG.pdf

J Gerontol A Biol Sci Med Sci. 2008 Jan;63(1):3-11.
Progressive diastolic dysfunction in the female mRen(2). Lewis rat: influence of salt and ovarian hormones.
Groban L, Yamaleyeva LM, Westwood BM, Houle TT, Lin M, Kitzman DW, Chappell MC.
SourceDepartment of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, NC 27127-1009, USA. lgroban@wfubmc.edu
Abstract

This study determined the contribution of chronic salt loading and early loss of ovarian hormones on diastolic function in the hypertensive female mRen(2). Lewis rat, a monogenetic strain that expresses the mouse renin-2 gene in various tissues. Estrogen-intact mRen2 rats fed a high salt (HS) (8% sodium chloride) diet exhibited early diastolic dysfunction when compared to normal salt-fed (NS) (1% sodium chloride) rats. In contrast, ovariectomized (OVX) rats on either NS or HS diets showed impaired relaxation with evidence of elevated left ventricular filling pressures (E/e') or pseudonormalization. This more advanced stage of diastolic dysfunction was associated with increases in interstitial cardiac fibrosis and high circulating levels of aldosterone, two factors leading to reduced ventricular compliance. These findings may explain the preponderance of diastolic dysfunction and diastolic heart failure in postmenopausal women and provide a potential animal model for evaluating prevention and treatment interventions for this disorder.- http://www.ncbi.nlm.nih.gov/pubmed/18245755

Thank you

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